Salary: £50,000 plus private medical cover, life assurance, and company pension
Location: London Bridge
Working Hours: 40 hours per week
Richmond Pharmacology is the UK’s largest early Phase Contract Research Organisation (CRO) conducting pioneering early phase healthy and patient volunteer trials. Our experienced and world-renowned team, our central London location and our global reach contribute to making Richmond Pharmacology an exciting and dynamic place to work.
We have a great opportunity for Clinical Pharmacology Scientists to join our Advanced Research Science team, contribute to our innovative work and expand their existing skills within the clinical pharmacology sector.
Responsibilities: You will work within Richmond Pharmacology’s Advanced Research team, reporting to the Director of Study Management, and you will liaise closely with Principal Investigators, internal medical team, pharmaceutical sponsors, regulatory authorities and other stakeholders to progress research programs of new medicines.
You will be responsible for supporting strategic and resourceful input into the design of innovative early phase clinical trials including pharmacokinetics and pharmacodynamics modelling and optimisation, dose selection/progression, risk analysis and exploring the role of biomarkers, with emphasis on translational pharmacology; as well as ensure guidelines within the industry are implemented and used innovatively for efficient scientific study design.
You will also be expected to ensure compliance, remain informed on regulations and developments in early phase clinical research, as well as maintain knowledge of product areas, current trends, and current literature.
Training: We expect you to have a good foundation for the role and you will also receive on-the-job training as well as any external training which is required for your career progression and/or enable you to carry out your tasks effectively as agreed.
- Working with industry leaders to design complex and adaptive clinical trial protocols including sections on the background to the new medicine, study objectives, eligibility criteria and safety considerations for first-time-in-man studies, appropriate methodology as well as evaluation of data.
- Understanding of pharmacokinetic, pharmacodynamic and safety analyses (including modelling and simulation) and able to apply these in the design, interim and final reporting of clinical trials as well as manuscripts, posters and presentations; including presenting tables and figures in a concise format to illustrate the key outcomes and conclusions from the study.
- Compile other clinical study documents to include, but are not limited to: Investigator brochures, Informed Consents, Safety summary reports, regulatory submissions and annual updates.
- Participate in cross-functional internal and external project team meetings, provide feedback to the Principal Investigator and other stakeholders on completed PK/PD and safety data analyses.
- Train and advice within the Advanced Research Science team on content and format requirements for various documents, as well as coordinate writing activities for document development (e.g. timelines and review/revision responsibilities) within the project teams.
- Contribute to authoring of conference abstracts and manuscripts for publication in high impact peer-reviewed journals.
- Timely completion of tasks to enable project implementation and achieve objectives according to agreed timelines and budget.
Competencies: Candidates applying for this role must have:
- A minimum of 3-4 years’ experience in any scientific role where you have gained competencies and good writing skills, ideally in a clinical trials environment; to enable you to understand the underlying principles of pharmacology and compile strategically focussed clinical trial documents.
- A life science degree, PhD or MD with publication experience including first author of a minimum of two peer-reviewed manuscripts.
- Proficiency in expert use of a range of resources (e.g. Microsoft office, scientific databases, referencing software, online submissions & tracking).
- The ability to effectively train and manage less experienced Clinical Pharmacology Scientist Associates, leading by example, is a team player, recognising where s/he can use his/her skills to support colleagues and direct reports.
- Strong interpersonal skills including excellent time management, decision making, presentation skills and communication skills.
Please provide both CV and a covering letter, the covering letter should include your availability, suitability for the post, interest in the role and eligibility to work in the UK.
Only candidates short-listed will be contacted.